15 Truly Non-Toxic Nail Polish Brands (2025)

What are the toxic chemicals commonly found in nail polish?

“The Toxic Trio”

• Formaldehyde: This known carcinogen isn’t just used in nail polish – it’s also found in embalming fluid. Regular exposure can trigger respiratory problems, and severe allergic reactions, and has been linked to several types of cancer.
• Toluene: A solvent that creates that smooth, glossy finish but comes at a cost. This nervous system disruptor can cause headaches and dizziness, and impact reproductive health, making it especially concerning for pregnant women. Chronic exposure due to solvent abuse can result in permanent neuropsychiatric effects.
• Dibutyl Phthalate (DBP): While it helps prevent polish from becoming brittle, this endocrine disruptor can interfere with hormone function. Studies have linked it to reproductive issues and developmental problems.

More Harmful Chemicals

• Formaldehyde Resin: A close cousin to formaldehyde that helps polish adhere to nails. Known to cause severe skin irritation and allergic reactions, it can also lead to breathing difficulties and chronic respiratory issues.
• Camphor: Known to strip essential nutrients from nails and prolonged exposure may lead to seizures, disorientation, and other neurological effects.
• Triphenyl Phosphate (TPHP): A known endocrine disruptor, it can interfere with hormone regulation, potentially affecting reproduction and development.
• Xylene: This solvent can irritate the skin, eyes, and respiratory system. It is also flagged as potentially carcinogenic, raising concerns about long-term exposure.
• Ethyl Acetate: A common solvent that can cause irritation to the eyes, stomach, and respiratory system if inhaled or absorbed through the skin.
• Methyl Methacrylate (MMA): Linked to respiratory issues, including asthma and loss of smell, it can also cause skin irritation and long-term health complications.

So, how is non-toxic nail polish different?

Non-toxic nail polish is revolutionizing how traditional nail polish is made.

By adopting a ‘free-from’ philosophy, non-toxic nail polish brands are deliberately eliminating the toxic chemicals and harsh solvents found in most conventional nail polishes.

The most toxic chemicals found in most nail polishes are known as the “toxic trio” (formaldehyde, toluene, and dibutyl phthalate).

The cleaner formulas used to make non-toxic nail polish steer clear of these dangerous chemicals along with other concerning ingredients like formaldehyde resin, camphor, and synthetic dyes. 

Instead, they embrace safer alternatives like natural minerals for color, plant-based ingredients for shine, and water-based solutions for easier application and removal.

What should I look for in a good non-toxic nail polish?

Remember when we used to just pick nail polish solely based on color? Those days are gone! Now you’ll spot labels like “3-Free,” “5-Free,” and even “10-Free” on polish bottles. But what do these numbers really mean?

Think of these labels as levels of clean beauty commitment. As the numbers climb, more concerning ingredients get the boot.

• “3-Free” polishes don’t include the toxic trio discussed earlier. 
• “5-Free” takes it further by also eliminating formaldehyde resin and camphor. 
• “10-Free” formulas typically eliminate additional toxic ingredients like parabens, xylene, and ethyl tosylamide.
• “21-Free” nail polish refers to a formulation that excludes 21 potentially toxic or harmful ingredients, including triphenyl phosphate (TPHP), benzophenone-1, and styrene.

Look For Safer Natural Ingredients 

But safer polish isn’t just about what’s missing – it’s also about what’s included. 

Look for formulas that harness the power of natural minerals for color, incorporate strengthening ingredients like vitamin E and wheat protein, and use water-based solutions instead of harsh solvents. 

Brand Transparency

Brand transparency should also be a top priority when choosing a non-toxic polish.

The most trustworthy companies won’t just slap a “natural” label on their products – they’ll provide clear, comprehensive ingredient lists, explain their manufacturing processes, and openly share their safety testing methods.

Read The Ingredients Label 

When it comes to reading labels, don’t let pretty packaging or buzzwords sway you. Take time to actually read the ingredient list, not just the “X-Free” claims on the front. 

Watch out for vague terms like “fragrance” or “parfum,” which can hide numerous undisclosed chemicals. 

What are the benefits of using non-toxic nail polish?

Safer Ingredients for a Healthier You

Non-toxic nail polishes omit toxic ingredients like formaldehyde, toluene, and DBP, preventing potential absorption and reducing health risks.

Plus, many non-toxic brands are vegan and cruelty-free, so you can feel good about your purchase from an ethical standpoint, too.

Nourish and Strengthen Your Nails

But the benefits don’t stop there. Non-toxic nail polishes are often enriched with vitamins, minerals, and natural extracts that nourish and strengthen your nails, promoting healthy growth and preventing brittleness. 

And thanks to advanced formulas, you don’t have to sacrifice performance for safety. These polishes deliver long-lasting, chip-resistant, and high-shine results that rival traditional salon brands.

Environmentally Friendly Approach

What’s more, non-toxic nail polish brands are leading the charge in sustainability, using eco-friendly packaging, and renewable ingredients, and implementing recycling programs to minimize their environmental impact. 

Some even offer inclusive options like halal-certified and wudu-friendly formulas, making nail care accessible to those with religious requirements.

Are non-toxic nail polishes safe for pregnant women?

Most water-based and “free-from” nail polishes are generally considered safe during pregnancy, though formulas vary by brand.

Here are major things to check:

• Look for brands labeled “pregnancy-safe” or “maternity-safe”.
• Avoid formulas containing formaldehyde, toluene, or DBP.
• Check for MADE SAFE or EWG-verified certifications.
• Always consult your healthcare provider first.

How long do non-toxic nail polishes typically last?

Generally, a well-applied non-toxic nail polish can last anywhere from 5 to 7 days. However, with careful application and maintenance, you may be able to extend it even longer.

Here are some things that might affect how long your manicure lasts when wearing non-toxic nail polish:

• Brand & Formula: Some non-toxic brands offer long-lasting formulas that can rival traditional polishes.
• Application Technique: Proper application, including using a good base coat and top coat, can significantly extend the life of your manicure.
• Nail Health: Healthy nails are more likely to hold onto polish longer.
• Daily Activities: Activities that involve frequent handwashing or exposure to water can shorten the lifespan of a manicure.   

If you’re looking for longer-lasting results, consider exploring “5-free” or “7-free” non-toxic polishes, which often have improved durability. 

Additionally, using a high-quality top coat can help seal in the color and protect against chipping.

Can I use a regular base and top coats with non-toxic nail polish?

While it’s possible to mix conventional and non-toxic products, the best results come from using matching systems designed to work together.

• Check manufacturer recommendations before mixing.
• Consider investing in a complete non-toxic system.
• Keep in mind that some formulas may affect breathability when mixed.

Do non-toxic nail polishes come in gel formulas?

While traditional UV-cured gel polishes typically contain harsh chemicals, many non-toxic brands now offer “gel-like” alternatives that provide similar shine and durability without requiring UV lamps.

These formulas combine the best of both worlds: 

• No UV/LED lamp is required.
• Gentler removal process.
• Options include plant-based alternatives and quick-dry formulas.